The role of genistein and melatonin in the correction of vasomotor symptoms, sleep disorders and the prevention of osteoporosis during perimenopause [ГЕНИСТЕИН И МЕЛАТОНИН В КОРРЕКЦИИ ВАЗОМОТОРНЫХ СИМПТОМОВ, НАРУШЕНИЙ СНА И ПРОФИЛАКТИКА ОСТЕОПОРОЗА В ПЕРИМЕНОПАУЗЕ]

To analyze the data available in the literature on the problem of correcting vasomotor symptoms and sleep disorders with genistein- and melatonin-containing complexes during the menopausal transition, foreign and Russian works published in the past two decades were sought in the international citation system PubMed. The mutual influence of menopausal symptoms and sleep disorders was found in menopausal women; the data from studies of the efficiency of therapy aimed at improving sleep quality and reducing menopausal symptoms with the drugs containing melatonin and phytoestrogens were systematized. It was noted that it was expedient to co-use alternatives for restoring sleep and reducing menopausal vasomotor symptoms, vitamin D in combination with calcium in order to prevent osteoporosis. © 2019 Bionika Media Ltd.. All rights reserved.