The failure of the pelvic floor (NTD) is a common syndrome in the modern female population, in which there is a combined or isolated prolapse of the pelvic floor and pelvic organs. In the study, tissues of the vaginal walls of 20 patients were studied by pelvic floor failure using light microscopy, PCR diagnostics, and immunohistochemistry before and after treatment with contact diathermy method. The results of the study of the material obtained after a course of diathermic treatment indicate compensation of chronic oxidative stress at the molecular level by leveling the imbalance of collagen and elastin and restoring the architectonics of the vaginal wall. © 2019, Advanced Scientific Research. All rights reserved.