The article deals with regional features of technology transfer within APEC (Asian-Pacific Economic Cooperation) member economies taking into consideration different institutional structures (government, regional authorities, scientific, educational, and industrial institutions.) The authors have performed analysis of opportunities for significant economic and technological development based on implementation of regional programs of technical and technological integration of Asian and Pacific region countries, showing quick economic growth due to increase of productive capacity, qualification level of personnel, accompanied with substantial amounts of investments into real sectors of economy, and large-scale implementation of state of-the-art technologies. Details of forming of different integration models within the region under question: Japan, China, South Korea, Singapore, Taiwan, are studied. Key elements of creation and development of the technology transfer systems from Asian and Pacific leaders in field of technology are provided. The authors use system approach, comparative and statistical analysis in their work. The study describes opportunities for significant economic and technological development based on implementation of regional programs of technical and technological integration of Asian and Pacific region countries. The article contains also a conclusion concerning perspectives of development of global economy on the basis of efficient unlocking of the potential of major regional economic zones, including the ones of the Asian and Pacific region. © 2017, ASERS Publishing House. All rights reserved.