The forms and directions of innovation cooperation of East Asian countries with Russia are the subject of the presented research. The aim of the work is an analysis of the innovative integration of Russia and East Asian countries – China, Japan and South Korea, its involvement in innovation processes of global, regional and cross-regional development. The research has confirmed the hypothesis that implementation of innovation strategy of a modern state involves both technological and social innovations, transposed into global innovation mechanisms of relations, including regional and cross-regional. The forecast of development of innovative integration directions between Russia and East Asian countries has been carried out. The main obstacles to its implementation have been noted.