Crystal strucutre of rac-methyl (11aR∗,12S∗,13R∗,15aS∗,15bS∗)-11-oxo-11,11a,12,13-tetrahydro-9H,15bH-13,15a-epoxyisoindolo[1,2-c]pyrrolo[1,2-a][1,4]benzodiazepine-12-carboxylate

The title compound, C21H18N2O4, obtained as a racemate, contains a novel heterocyclic system, viz. isoindolo[1,2-c]pyrrolo[1,2-a][1,4]benzodiazepine. The central diazepane ring has a distorted boat conformation with two phenylene-fused and one methine C atom deviating by 0.931(1), 0.887(1) and 0.561(1)Å, respectively, from the mean plane of the rest of the ring. The γ-lactone ring has an envelope conformation, with the C atom opposite to amide bond deviating by 0.355(1)Å from its plane. In the crystal, molecules form centrosymmetric dimers through pairs of C-H⋯O hydrogen bonds. © 2014.

Авторы
Zaytsev V.P. 1 , Orlova D.N. 1 , Gurbanov A.V.2 , Zubkov F.I. 1 , Khrustalev V.N. 3
Номер выпуска
12
Язык
Английский
Страницы
o1225-o1226
Статус
Опубликовано
Том
70
Год
2014
Организации
  • 1 Organic Chemistry Department, Peoples' Friendship University of Russia, Miklukho-Maklaya St 6, Moscow, 117198, Russian Federation
  • 2 Baku State University, Z. Khalilov St 23, Baku, AZ-1148, Azerbaijan
  • 3 X-Ray Structural Centre, A.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 Vavilov St, Moscow, 119991, Russian Federation
Ключевые слова
benzodiazepines; crystals structure; hydrogen bonds; IMDAF reaction; isoindolylpyrroles
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