Objective. To study the possibilities of predicting the risks of abnormal and massive blood loss during preterm labor on the basis of the causes of bleeding. Material and methods. The authors carried out a prospective analysis of 1442 deliveries complicated by bleeding. Discriminant analysis was made to classify intergroup differences in the presence of abnormal and massive blood loss and in the absence of bleeding during preterm and term labor. Resu1ts. The relative risk of abnormal or massive blood loss on the basis of the causes of bleeding in preterm labor; the signs determining intergroup differences in the presence of abnormal and massive blood loss and in the absence of bleeding during preterm and term labor; and the signs indicating the risks of hypotonic bleeding were assessed. Conclusion. Preterm labor is threatened by abnormal and massive blood loss. The structure of the main causes of abnormal and massive blood loss is different in preterm and term labor, which leaves a resource to choose preventive and therapeutic measures. © 2019, Bionika Media Ltd. All rights reserved.