Background/Objectives: In 2015 the international community adopted a new agenda for sustainable development for the period of 2016-2030- Sustainable Development Goals (SDGs). In the article, authors critically analyzed some of SDGs. Methods: The article used scientific methodological approach, which facilitates to determine the whole canvas of the research, identify the main aspects and concepts of the study. The research used scientific methods of cognition, i.e., dialectics, analysis, and synthesis, the method of generalization and system-structural method. The article also practiced special methods of science such as legal and technical, historical and forecasting methods. Findings: In this article, the authors critically analyze the SDGs with a view to determine problematic aspects of their implementation in the field of human rights protection, environmental protection, disaster risk reduction and management of migration and suggest ways to overcome these obstacles. Authors made many recommendations in these spheres. At the present stage, in the framework of global efforts aimed at the implementation of the SDGs, it is important to pay more attention to the mechanisms for monitoring the achievement of the goals. In this sense, a compliance review at the level of inter-regional, regional and sub-regional organizations can make a significant contribution and provide diversified, reliable and proven tools to assess progress in achieving the SDGs. Such reviews will identify regional trends, causes of problems, and similarities; they will facilitate the exchange of best practices, lessons learned and development of solutions and measures of mutual support at the global level, taking into account specific regional and sub-regional needs. Application/Improvements: The results could be used by UN bodies, inter-regional, regional and sub-regional organizations, ministers of States and other relevant stakeholders, which implements SDGs.