This article discusses the quality of life and psychological state in persons undergoing a coronary artery bypass surgery (CABG), in the dynamics of physical rehabilitation. We study the interrelationships of quality of life, psychological state with the level of tolerance to physical activity. The analysis of indicators of quality of life in the main areas and psychological state, taking into account personal and situational anxiety, in patients at different stages of rehabilitation, which allowed to identify the characteristics of the dynamics of the studied parameters in groups of people with different tolerance to physical activity. The novelty lies in the fact that direct relationships have been found between the level of exercise tolerance and the quality of life, the psychological state of those who have undergone CABG surgery. Methods. Evaluation of the quality of life of the surveyed was carried out using the Russian version of the World Health Organization questionnaire WHOQOL-100 (100 questions), designed to assess the quality of life (QOL) of the adult Russian-speaking population in Russia and other countries (WHOQOL Group, 1993) [1]. The level of situational and personal anxiety was assessed using the Spielberger-Khanin questionnaire. Exercise tolerance was assessed using a Six Minute Walk Test (SMWT). Results. The study involved men (n = 60) who underwent CABG surgery. It has been established that in patients with a decrease in exercise tolerance, the overall indicator of quality of life decreases and situational and personal anxiety increases. The discussion of the results. It is concluded that it is necessary to create individual approaches in physical and psychological rehabilitation for people with different levels of exercise tolerance at all stages of rehabilitation.