Dependence of Anterior Active Rhinomanometry Indices on Nasal Obstructive Disorders in Children with Atopic Bronchial Asthma Complicated by Nasal Symptoms

Background. Atopic bronchial asthma (BA) in children is associated with upper airways pathology (UAP). Among them, a combination of allergic rhinitis (AR) and nasal obstructive disorders (NOD), including hypertrophy of the pharyngeal tonsil (HPT) and anomalies of the intranasal structures (AINS), is abundant. In such patients, anterior active rhinomanometry (AARM) is an important method of examining nasal patency. However, NOD can influence the AARM parameters in children with BA and nasal symptoms, and this effect must be taken into account in clinical practice. Study goal was to elucidate the effect of NOD on rhinomanometric parameters in this group of patients. Methods. Total of 66 children with BA and AR were examined with AARM, rhinovideoendoscopy, spirometry, and standard clinical tests allowing revealing the structure of comorbid pathologies. In order to avoid the influence of anthropometric parameters of children and their age on AARM parameters, a special index of reduced total nasal airflow was used. Results. It has been established that NOD, especially HPT, have a significant negative impact on the indices of anterior active rhinomanometry during the periods of both AR remission and AR exacerbation. The effect of AINS is much weaker and was remarkable only in combination with HPT. © 2018 Tatyana I. Eliseeva et al.

Авторы
Eliseeva T.I.1 , Krasilnikova S.V.2 , Babaev S.Y.1, 2 , Novozhilov A.A.4 , Ovsyannikov D.Y. 5 , Ignatov S.K.6 , Kubysheva N.I.7 , Shakhov A.V.4
Издательство
Hindawi Limited
Язык
Английский
Статус
Опубликовано
Номер
1869613
Том
2018
Год
2018
Организации
  • 1 Hospital Pediatrics, Privolzhsky Research Medical University, 10/1 Minin and Pozharsky Square, Nizhny Novgorod, 603005, Russian Federation
  • 2 Department of ENT Diseases, Privolzhsky Research Medical University, 10/1 Minin and Pozharsky Square, Nizhny Novgorod, 603005, Russian Federation
  • 3 MD, Department of ENT Diseases, Privolzhsky Research Medical University, 10/1 Minin and Pozharsky Square, Nizhny Novgorod, 603005, Russian Federation
  • 4 MD, Head of the Department of ENT Diseases, Privolzhsky District Medical Center of Federal Medico-Biologic Agency of Russia, 2 Nizhne-Volzhskaya Naberezhnaya, Nizhny Novgorod, 603005, Russian Federation
  • 5 Department of Pediatrics, Medical Institute, Peoples' Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya St, Moscow, 117198, Russian Federation
  • 6 Photochemistry and Spectroscopy, Lobachevsky State University of Nizhny Novgorod, 23 Gagarin Avenue, Nizhny Novgorod, 603950, Russian Federation
  • 7 Med. Info. Res. Laboratory of the Higher School of Information Technologies and Information Systems, Kazan Federal University, 18 Kremlyovskaya St, Kazan, 420000, Russian Federation
Ключевые слова
adolescent; allergic asthma; anthropometric parameters; Article; asthma; child; disease exacerbation; disease severity; female; forced expiratory volume; human; major clinical study; male; nose airflow; nose cavity; nose disease; nose obstruction; remission; respiratory function; rhinomanometry; spirometry; symptomatology; videoendoscopy
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