Immunohistochemical features of breast fibroadenomas

9 breast fibroadenomas from females of different age who had a familial history of breast cancer were immunohistochemically studied. Having the same histological structure, the tumors differed in the expression of steroid hormone receptors, in the values of proliferation marker Ki-67 and oncomarker p53. It is concluded that the study of fibroadenoma may reveal breast carcinoma risk groups.