Quantitative determination of metabolites in human urine by 1 H NMR spectroscopy

Conditions for registration of urinary 1H NMR spectra have been optimized in order to achieve maximal accuracy of quantitative analysis. Urinary samples from patients with acute pancreatitis have been investigated and spectral data of identified urinary metabolites and results of their quantitative determination are given. Employment of 1H NMR spectra is perspective for the development of new laboratory diagnostic methods. © MAIK Nauka 2008.