Participation of endotoxin from gram-negative bacteria in mechanisms of regulation of thyroid status

Alteration of thyroid hormone blood levels in rats in different periods after exposure of high dose of lipopolysacchari.de from E. coli were studied. Direct inhibition of thyroid function without hypothalamuspituitary dysfunction is revealed. High dose by high doses of bacterial endotoxin leads to changes in rat thyroid status caused by both hypothalamus-pituitary and thyroid hypofunction. endotoxin, gramnegative bacteria, thyroid hormone.

Авторы
Yaglova N.V.1 , Berezov T.T. 2
Журнал
Voprosy Pitaniia
Номер выпуска
3
Язык
Русский
Страницы
18-23
Статус
Опубликовано
Ссылка
Внешняя ссылка
Том
79
Год
2010
Организации
  • 1 Institute of Human Morphology, Russian Academy of Medical Sciences, Moscow, Russian Federation
  • 2 Russian University of People's Friendship, Moscow, Russian Federation
Ключевые слова
lipopolysaccharide; lipopolysaccharide, E. coli 026 B6; lipopolysaccharide, E. coli 026-B6; lipopolysaccharide; animal; article; dose response; Escherichia coli; hypothalamus hypophysis system; male; metabolism; pathology; pathophysiology; rat; thyroid gland; Wistar rat; hypothalamus hypophysis system; metabolism; pathology; thyroid gland; toxicity; Animals; Dose-Response Relationship, Drug; Escherichia coli; Hypothalamo-Hypophyseal System; Lipopolysaccharides; Male; Rats; Rats, Wistar; Thyroid Gland; Animals; Dose-Response Relationship, Drug; Escherichia coli; Hypothalamo-Hypophyseal System; Lipopolysaccharides; Male; Rats; Rats, Wistar; Thyroid Gland
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