Possibility of using near-IR spectrometry for drug quality control with respect to dose uniformity

The possibility of applying near-IR spectroscopy for drug quality control with respect to dose uniformity was studied. Methods for the calibration and determination of the content of active ingredients in model drugs with various mass fractions of the active ingredient were developed. Statistical processing of the results showed that both methods give reproducible results and do not introduce systematic errors. © 2011 Springer Science+Business Media, Inc.