Correlation between expression of androgen receptors and the degree of cell differentiation in human prostate cancer [Sootnoshenie mezhdu ékspressiei retseptorov k androgenam i stepen'iu differentsirovki pri rake predstatel'noi zhelezy cheloveka.]

Immunohistochemical examination was carried out to investigate androgen receptor antigen expression in epithelial cells of benign or malignant tumors in the prostate of aged men. The benign tumors were characterized by homogeneous distribution of androgen receptors in all nuclei of secretory epithelial cells. In malignant cells there was partial or complete loss of the androgen receptors to androgens in parallel with decreased cell differentiation.