Back pain: empirical and personalized approach to drug therapy. Conclusion of the Expert Council of the Russian Society for the Study of Pain

Objective. To present the recommendations of the expert council of the Russian Society for the Study of Pain on “Dorsumio” drug in the treatment of chronic nonspecific back pain (CNBP). Key points. Currently, CNBP is the leading disease associated with disability worldwide. Patients with CNBP often experience concomitant depressive and anxiety symptoms complicating the course of disease and therapy, as well as worsening the quality of life and working capacity. Various problems in care for CNBP include not only the impact on pathogenesis of chronic pain, but also treatment of depression, anxiety, insomnia, assessment of compatibility of various drugs and patient adherence to therapy. The new drug “Dorsumio” (mirtazapine 15 mg + tizanidine 6 mg) can influence on chronic pain mechanisms and provide effective therapy for patients with chronic nonspecific back pain due to complex analgesic, muscle relaxant, antidepressant and anti-anxiety effects. © 2025, Media Sphera Publishing Group. All rights reserved.

Авторы
Kukushkin M.L. 1 , Amelin Aleksander Vitalevich 2 , Akhmedzhanova Louiza T. 3, 4 , Barantsevich Evgeny Robertovich 2 , Barulin Alexander Evgenievich 5 , Beniashvili Allan G. 6 , Davydov O.S. 1 , Danilov A.B. 3 , Devlikamova Farida I. 7 , Zhivolupov Sergey Anatolyevich 8 , Iskra D.A. 9 , Kamchatnov P.R. 10 , Karakulova Yu V. 11 , Karpova M.I. 12 , Kozlov Ivan Genrikhovich 3, 13 , Kurushina O.V. 5 , Rachin A.Petrovich 14 , Sivolap Yu P. 15 , Churyukanov Maxim V. 3, 16 , Shirokov V.A. 17 , Yakupov E.Z. 18
Номер выпуска
1
Язык
Русский
Страницы
92-98
Статус
Опубликовано
Том
23
Год
2025
Организации
  • 1 Institute of General Pathology and Pathophysiology RAMS, Moscow, Moscow Oblast, Russian Federation
  • 2 Pavlov University, Saint Petersburg, Russian Federation
  • 3 Sechenov First Moscow State Medical University, Moscow, Russian Federation
  • 4 Academy of Medicine, Moscow, Russian Federation
  • 5 Volgogradskij Gosudarstvennyj Medicinskij Universitet, Volgograd, Volgograd Oblast, Russian Federation
  • 6 Federal State Budget Scientific Institution "Scientific Center of Mental Health", Moscow, Moscow Oblast, Russian Federation
  • 7 Kazan State Medical Academy, Kazan, Tatarstan Republic, Russian Federation
  • 8 Military Medical Academy, Saint Petersburg, Saint Petersburg, Saint Petersburg, Russian Federation
  • 9 Saint Petersburg State Pediatric Medical University, Saint Petersburg, Leningrad Oblast, Russian Federation
  • 10 Pirogov Russian National Research Medical University (RNRMU), Moscow, Russian Federation
  • 11 E.A.Vagner Perm State Medical University, Perm, Permskaja Oblast, Russian Federation
  • 12 South Ural State Medical University, Chelyabinsk, Chelyabinsk Oblast, Russian Federation
  • 13 Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Moscow Oblast, Russian Federation
  • 14 National Association of Experts in Comorbid Neurology, Moscow, Moscow, Russian Federation
  • 15 RUDN University, Moscow, Moscow Oblast, Russian Federation
  • 16 Petrovsky National Research Centre of Surgery, Moscow, Russian Federation
  • 17 Ural State Medical University, Yekaterinburg, Sverdlovskaya, Russian Federation
  • 18 Yakupov’s Neuroclinic, Professor Yakupov Neuroclinic and Education Center, Kazan, Russian Federation
Ключевые слова
central muscle relaxants; chronic nonspecific back pain; “Dorsumio”
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Kukushkin M.L., Amelin Aleksander Vitalevich, Akhmedzhanova Louiza T., Barantsevich Evgeny Robertovich, Barulin Alexander Evgenievich, Beniashvili Allan G., Davydov O.S., Danilov A.B., Devlikamova Farida I., Zhivolupov Sergey Anatolyevich, Iskra D.A., Kamchatnov P.R., Karakulova Yu V., Karpova M.I., Kozlov Ivan Genrikhovich, Kurushina O.V., Rachin A.Petrovich, Sivolap Yu P., Churyukanov Maxim V., Shirokov V.A. ...
Российский журнал боли. Том 23. 2025. С. 92-98