On the toxicity of dimethylcyanamide (Russian)

Dimethylcyanamide (DMC) is a highly poisonous compound with diverse modes of its introduction into the organism. For mice (with gastric introduction) LD50 = 73 mg/kg; for rats and guinea pigs it amounts to 146; for mice LD50 (skin) is 125 mg/kg. For mice LC50 is 2800 mg/m3, for rats 2500 mg/m3. Lim(ac) for mice and rats is 100 mg/m3. The compound displays a very poorly marked functional cumulation. The mechanism of its action is analogous to that of inorganic cyanamides. As a tentatively safe level of action a concentration of 0.5 mg/m3 is recommended.