Use of Neuroendoscopy in Combination Treatment of a Three-Year-Old Patient With Primary Disseminated Medulloblastoma: A Case Report

A three-year-four-month-old boy with primary disseminated medulloblastoma M3 stage and secondary occlusive hydrocephalus underwent an endoscopic triventriculocisternostomy (ETVC) and tumor biopsy, followed by ventriculoperitoneal shunt (VPS) placement due to ETVC failure. The treatment regimen, which included intensive induction chemotherapy, proton beam therapy (PBT), and maintenance chemotherapy, led to significant clinical improvement and a complete radiological response. Four years post-treatment, the child remains in remission, illustrating the effectiveness of a multimodal approach in managing complex cases of medulloblastoma in pediatric patients.

Авторы
Ashurov J.A. 1, 2 , Musa G. 1, 3 , Kumirova E. 4 , Margaryan S.N. 5 , Livshitz M.I. 2 , Ozerov S.S. 2 , Soto G.R. 6 , Ramirez M.DE. 2, 7 , Chmutin G.E. 2, 7
Издательство
SPRINGERNATURE
Номер выпуска
8
Язык
Английский
Статус
Опубликовано
Номер
e68239
Том
16
Год
2024
Организации
  • 1 Peoples Friendship Univ Russia, Neurol Dis & Neurosurg, Moscow, Russia
  • 2 Morozovskaya Childrens City Clin Hosp, Neurosurg, Moscow, Russia
  • 3 Livingstone Cent Hosp, Neurosurg, Livingstone, Zimbabwe
  • 4 Morozovskaya Childrens City Clin Hosp, Pediat Oncol, Moscow, Russia
  • 5 Morozovskaya Childrens City Clin Hosp, Oncol, Moscow, Russia
  • 6 Mex Natl Canc Inst, Neurosurg Oncol, Tlalpan, Mexico
  • 7 Peoples Friendship Univ Russia, Neurosurg, Moscow, Russia
Ключевые слова
pediatric oncology; endoscopic biopsy; brain tumor; medulloblastoma; ventriculoperitoneal shunt; etv
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