Кандидоз у новорожденных: новые решения старой проблемы (обзор литературы)

Candidiasis in Newborns: New Solutions to a Longstanding Challenge (a Literature Review)

Candidiasis in newborns (ICD-10: P37.5) is an infectious disease caused by fungi of the genus Candida, affecting various organs and systems. Given the widespread prevalence of candidiasis, an increase in its incidence in newborns has been observed in recent years. Localized forms occur in approximately 20%of children, while generalized forms occur in an average of 3%of newborns. In most cases, the disease is secondary in nature and is associated with prematurity, extremely low birth weight, the mother’s or child’s use of certain medications during pregnancy, immunodeficiency, invasive procedures, and a number of other circumstances. The study of candidal infection in newborns is particularly important due to the fact that its clinical manifestations are largely non-specific and can mimic a wide range of diseases. This necessitates a thorough differential diagnosis involving specialists from various fields. The rare occurrence of invasive neonatal candidiasis, the variability of its clinical course and risk factors, as well as its high mortality rate, underscore the relevance of summarizing current data on the pathogen, the characteristics of its pathogenesis, diagnostic approac hes and therapeutic strategies for this pathology in newborns. © 2025, Professionalnye Izdaniya. All rights reserved.