Talc deposits found in the southwestern Fodikwan area of northeastern Sudan exhibit potential economic significance; nevertheless, their geological context, geochemical characteristics, and genesis remain inadequately defined. This study aims to elucidate the origin and formation mechanisms of these deposits, thereby facilitating the development of more effective exploration strategies. An integrated methodology was employed, comprising detailed geological mapping, petrographic investigations, and mineralogical and geochemical assessments utilizing X-ray diffraction (XRD) and X-ray fluorescence (XRF). The study area is characterized by basement rocks comprising a volcanic-sedimentary sequence that has been metamorphosed in the greenschist facies and intruded by syn-to late-orogenic microgranodiorite. Field and petrographic observations indicate that unaltered dolomitic marble predominates in areas distant from microgranodiorite contacts. Conversely, the contact zone between dolomitic marble and microgranodiorite presents a conducive environment for talc mineralization. Geochemical analyses reveal that SiO