Tophaceous gout masquerading as lumbar disc herniation: Case report

Background: Spinal gout is a rare condition that frequently mimics common spinal disorders such as lumbar disc herniation, leading to diagnostic challenges and misdiagnosis. We report a case of spinal gout presenting as lumbar radiculopathy, ultimately confirmed through histopathological analysis. Case: A 66-year-old man with a known history of gout and hypertension came to the hospital with a right L5 radiculopathy and right ankle dorsiflexion weakness graded as 3/5. Magnetic resonance imaging suggested a right paracentral disc herniation with nerve root compression. The patient underwent surgical decompression and spinal stabilization, during which abnormal tissue was excised and submitted for pathological examination. Results: Histopathological analysis confirmed the diagnosis of gouty tophus. Following surgery, the patient experienced rapid symptomatic relief. His motor strength improved significantly to 5/5 at the two-week follow-up, and he regained full independent mobility without recurrence. Conclusion: Clinicians should consider spinal gout in the differential diagnosis of lumbar radiculopathy, particularly in patients with a history of gout, as histopathological confirmation is essential for accurate diagnosis and effective management. © 2025 The Author(s)

Авторы
Chérubin Tshiunza Mpoyi 1, 2 , Mukengeshay Ntalaja Jeff 3 , Goert Mirenge 3 , Guelord Metre 3 , Reyes-Soto Gervith 4 , López-Elizalde Ramiro 5 , Gok Egemen 6 , Yangi Kivanc 7 , Encarnacion Ramirez Manuel De Jesus 4, 8, 9 , Bozkurt Ismail 10, 11
Издательство
Elsevier B.V.
Язык
Английский
Статус
Опубликовано
Номер
102183
Том
43
Год
2026
Организации
  • 1 Department of Neurosurgery, HJ Hospital, Kinshasa, Kinshasa, Democratic Republic Congo
  • 2 Department of Neurosurgery, Université de Mbujimayi, Mbujimayi, Democratic Republic Congo
  • 3 Department of Neurosurgery, Centre Hospitalier Initiative Plus, Kinshasa, Democratic Republic Congo
  • 4 Department of Head and Neck, Instituto Nacional de Cancerologia, México, Tlalpan, DF, Mexico
  • 5 Secretaria de Salud, Acapulco, GRO, Mexico
  • 6 Hacettepe Üniversitesi, Ankara, Turkey
  • 7 Department of Neurosurgery, Prof. Dr. Cemil Tascioglu City Hospital, Istanbul, Istanbul, Turkey
  • 8 Department of Neurological Surgery, RUDN University, Moscow, Moscow Oblast, Russian Federation
  • 9 Institute of Clinical Medicine Named After N.V. Sklifosovskiy, Moscow, Moscow, Russian Federation
  • 10 Department of Neurosurgery, Ankara Numune Hospital, Ankara, Turkey
  • 11 Department of Neurosurgery, Yüksek İhtisas Üniversitesi, Ankara, Turkey
Ключевые слова
Disc herniation; Foraminal stenosis; Gout; Spinal stenosis; Tophus
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