On the clinical pharmacology of isoniazid (Literature survey)

Data of a comparative assessment of procedures for isoniazid phenotyping and acetylation as well as the significance of the nature of its metabolism in treating tuberculosis, and contemporary concepts as to the causes underlying the individual hepatotoxicity of the drug are discussed.

Авторы
Ivleva Ya.A.
Журнал
Problemy Tuberkuleza
Номер выпуска
1
Язык
Русский
Страницы
18-26
Статус
Опубликовано
Ссылка
Внешняя ссылка
Том
57
Год
1979
Организации
  • 1 Kaf. Farmakol., Med. Fak., Univ. Druzhby Narodov, Moscow
Ключевые слова
isoniazid; isoniazid; adverse drug reaction; drug comparison; drug induced disease; drug metabolism; drug therapy; drug toxicity; intoxication; liver; pharmacokinetics; respiratory system; therapy; tuberculosis; acetylation; clinical trial; comparative study; drug effect; drug screening; ethnic group; female; human; individuality; liver; lung tuberculosis; male; metabolism; pharmacogenetics; phenotype; review; time; Acetylation; Clinical Trials; Comparative Study; Drug Evaluation; Ethnic Groups; Female; Human; Individuality; Isoniazid; Liver; Male; Pharmacogenetics; Phenotype; Time Factors; Tuberculosis, Pulmonary
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