Transition Metal‐Catalyzed C−H Activation/Annulation Approaches to Isoindolo[2,1‐b]isoquinolin‐5(7H)‐ones

AbstractThe isoindolo[2,1‐b]isoquinolin‐5(7H)‐one scaffold is widely present in lots of bioactive natural products. Diverse types of strategies have been developed to construct this scaffold. Recently, transition metal‐catalyzed C−H activation/annulation is emerging as a powerful and straightforward method to construct diverse polyheterocycles with high atom‐ and step‐economy. It also has been employed for the synthesis of the isoindolo[2,1‐b]isoquinolin‐5(7H)‐one scaffold. This review provides an introduction to recent advances for the preparation of isoindolo[2,1‐b]isoquinolin‐5(7H)‐ones by using transition metal‐catalyzed C−H activation/annulation. It will help researchers to find hidden opportunities and accelerate the discovery of novel transformations based on C−H activation/annulation.

Авторы
Tang Xiao1 , Ding Songtao1 , Song Liangliang2 , Van der Eycken. Erik V. 3, 4
Журнал
Издательство
John Wiley and Sons Inc
Номер выпуска
3
Язык
Английский
Статус
Опубликовано
Том
23
Год
2023
Организации
  • 1 College of Science Nanjing Forestry University Nanjing 210037 China
  • 2 Jiangsu Provincial Key Lab for the Chemistry and Utilization of Agro-Forest Biomass Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources Jiangsu Key Lab of Biomass-Based Green Fuels and Chemicals International Innovation Center for Forest Chemicals and Materials, College of Chemical Engineering Nanjing Forestry University Nanjing 210037, Jiangsu China
  • 3 Laboratory for Organic &amp
  • 4 Peoples' Friendship University of Russia (RUDN University) Miklukho-Maklaya Street 6 117198 Moscow Russia
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