Теоретическая концепция болезней цивилизации (экопастеровская теория современной патологии): взгляд в будущее

В работе предлагается новая концепция медицины и доказательства наличия связи между инфекционной реактивностью и недавно начавшейся и продолжающейся эпидемией болезней цивилизации. Впервые за всю историю человечества растут и болеют поколения с измененной цивилизацией реактивностью (нейро-иммунно-эндокринная система), которая в норме способствует развитию (регуляции) иммунной системы, воспаления, гормональной регуляции энергетического гомеостаза и тканевой регенерации. «Утрата» (диета, нестероидные препараты, БЦЖ и др.) этого древнего, доминантного и неизменного члена здоровья человека, несомненно, будет иметь последствия – эпидемия современных болезней.

Theoretical concept of diseases of civilization (ecopasteurian theory of modern pathology): a glimpse into the future

Examination of the state of medicine in the perspective of ecological imperatives and nonanthropocentric metaphysics prompts a new approach to current problems of health care (A.V. Pasechnik, 1985-2013). Whereas the early half of the 20th century was still an age of infectious diseases, mortality caused by them later declined by 99% and an "epidemic" of chronic noninfectious diseases (diseases of civilization) such as atherosclerosis, cancer, hypertension, diabetes, etc. set in. Vast accumulated data indicate no downtrend in incidence of these diseases despite the implementation of large - scale programmes of multifactor disease prevention. Awareness about the critical situation generates the need to search for conceptual alternatives, new theoretical explanations for this range of global problems that would account for the present - day "drift" of methodological approaches (the dialectio treatment of the problem, "complimentariness" in N. Bohr's sense, views of P.Feyerab'end, or Einstein's viewpoint emphasizing a free choice of theoretical postulates. The process of theoretical mastering of factual data has found its expression in a new conception (paradigm) of medicine. Concisely it can be summarized as follows: Disease as the infections process also contains the opposite truth, that of a natural form of self-care. A set of systemic reactions of the organism describing the development of infections processes is treated as realization of the natural "therapentic" mechanisms ("assimilation" of ordering from the environment) ensuring protection from the development of the diseases of civilization. By bringing the infections process to pase, the organism fulfils an expedient, system - forming activity essential for its vitality. The morpho - functional structure of the organism requires some periodic "sanitary" procedures conducive to liberating from the "substrate" of modern forms of diseases. Life process is included into the system of natural laws and is directed, organized and structured. Today me know that it were bacteria that hundreds of millions years ago constituted the initial biological system of the Earth. They formed the base upon which the entire complex "network" of the living matter developed. The strategy of wiping infectious diseases with time gives rise to its opposite, i.e. the development of autoimmune and allergic processes underlying the genesis of chronic noninfections diseases. Within this frame of reference the problem of diseases of civilization, is a consequence of taking the activity of curbing (negating) the infections reactivity beyond the limits of the admissible? The prime issue is to develop this new strategy of medicine; it is necessary to elaborate maximum permissible levels of using this sanogenic natural law. The fight against infectious disease advanced dramatically with the consolidation of the germ theory in the 19th century. This focus on a predominant cause of infections (i.e., microbial pathogens) ultimately led to medical and public health advances (eg, immunization, pasteurization, antibiotics). However, the resulting declines in infections in the 20th century were matched by a rise in chronic, noncommunicable diseases, for which there is no single underlying etiology. The discovery of a form of low-grade systemic and chronic inflammation (“metaflammation”), linked to inducers (broadly termed “anthropogens”) associated with modern fabricated environments and lifestyles, suggests an underlying basis for chronic disease that could provide a 21st-century equivalent of the germ theory.