Изучение стабильности таблеток мальвы лесной экстракта сухого

Изучена стабильность шипучих таблеток травы мальвы лесной экстракта сухого.

Investigations, held in All-Russian Research Institute of Medicinal and Aromatic plants showed the necessity of development of the tablets, with polysaccharides from Malva sylvestris herb. The goal of this work is studying of stability of effervescent tablets from Malva sylvestris dry extract. Methods of granulation and direct pressing for manufacturing effervescent tablets were used. While making tablets by the granulation method 10 % spirituous solution of polyvinilpirrolidon for humidifying was used. Into structure of tablets enters microcrystalline cellulose-90. For direct pressing method with the account of optimal technology characteristics excipient Emdex was select.Sodium hydrocarbonate and lemon acid were gas-making compounds. The stability of the tablets was studied with the use of physico-chemical, technological and microbiological methods of analysis for the following indicators: the appearance, authenticity, quantitative of polysaccharides, microbiological purity, average weight, deviation from average weight, disintegration, abradability, durability on compression was developed. The obtained results testify that tablets are stable in the course of storage during 24 months.