Тяжелое поражение глаза при синдроме Стивенса - Джонсона

В статье приводится случай наблюдения и лечения пациента с синдромом Стивенса-Джонсона, которому была произведена покровная кератопластика аллотрансплантатом и некровавая тарзорафия. При контрольном осмотре больного через полгода после выписки имелось сосудистое бельмо роговицы.

Case of severe Stevens Johnson syndrome: ocular sequel

Stevens-Johnson syndrome is a severe form of erythema multiforme with papules, vesicles, urticarial plaques and purpura of two mucous membranes or more. Cardiovascular, urinary and haemopoetic symptoms are rare. Eye symptoms in most patients have favorable outcome, but ocular sequelae may include corneal ulceration, endophtalmitis and eyeball atrophy. Drugs such as antibiotics, sulfanilamides, non-steriod anti-inflammatory remedies, anticonvulsants and analgesics are most often implicated as the etiology. There are few references on time of оnset, severity, relapse and treatment оf оcular symptoms оf Stevens-Johnson syndrome. The improper treatment can result in severe complications, including panophtalmitis and blindness.' We observed one patient with Stevens-Johnson syndrome. He was hospitalized in eye surgery department оf AMO ZIL Сlinic for three times: at first allergic keratoconjunctivitis was diagnosed, two months later he was hospitalized secondly with, symptoms of regional profound keratitis, and one month later for the third time with corneal ulceration. Integumentary allograft keratoplasty and tarsorrhafia were performed. Control examination 6 months later revealed corneal spot. Stevens-Johnson syndrome, erythema multiforme, keratoconjunctivitis, regional profound keratitis, corneal ulceration, integumentary allograft keratoplasty, tarsorrhafia, corneal spot.