ХРОНИЧЕСКИЙ ГЕПАТИТ С

Обзор исследований по гепатиту С, рассматривается патогенез инфекции, лечение ИНФв сочетании с рибавирином и другими лекарствами.

CHRONIC HEPATITIS C

Review concerns questions of history of investigation of non-A, non-B hepatitis (hepatitis C) and hepatitis C virus virology, updated diagnostic procedures and their meaning, biochemical, histological and immunological features of CH-C are also observed. Special attention to pathogenesis and natural course of chronic HCV-infection is paid. Detailed discussion on problem of treatment of CH-C by IFN-alpha, its combination with ribavirin and other drugs. Analysis of results of clinical trials gives hope on effectiveness of antiviral therapy. Predictors of response are important in choosing of protocols of antiviral teratment and determine possibility of complete response. Prospects in treatment of CH-C lay in combination of antiviral drugs.