Application of Mixing Indices in Modeling Processes in Pharmaceutical Production

Use of the discrete element method made it possible to make progress in modeling such a complex process as mixing. However, choosing a mixing index to evaluate the mixing efficiency of various excipients and pharmaceutical substances is a non-trivial task that makes the systematization and analysis of indices used for modeling critical. Mixing indices used in modern research on modeling the mixing process by the discrete element method starting from the Lacey index and ending with new methods applicable under fluidization conditions are discussed and analyzed.

Авторы
Markeev V.B.1 , Blynskaya E.V. 1, 2 , Tishkov S.V. 1 , Alekseev K.V. 1 , Alekseev V.K.1
Номер выпуска
3
Язык
Английский
Страницы
430-440
Статус
Опубликовано
Том
57
Год
2023
Организации
  • 1 Research Zakusov Institute of Pharmacology
  • 2 Peoples’ Friendship University of Russia
Ключевые слова
mixing; mathematical modeling; discrete element method; mixing indices; Lacey index; convection; diffusion; pharmacy; Pharmacology/toxicology; organic chemistry
Дата создания
01.07.2024
Дата изменения
01.07.2024
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/109374/
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