This article studies the development of regional economic cooperation between China and Russia in the new era. Northeast China and the Far East of Russia are both underdeveloped regions. Under the conditions of a market economy, it is difficult to achieve leapfrog development by relying solely on their rich resources, must rely on the strong support and effective promotion of national macroeconomic regulation and regional economic policies. Regional economic policy is an important component of national economic policy, and is also the core of the national macroeconomic control system for regional economic development. It aims to coordinate and promote regional economic development and ensure regional security. Promote high-quality development of Sino Russian economic and trade cooperation, and inject new impetus into comprehensively promoting bilateral cooperation.