Study of the stereochemistry of N-H and N-vinyl-4,5,7-trimethyi-4,5,6,7-tetrahydropyrrolo[3,2-c]pyridines and their nitro derivatives by the method of 1H and 13C NMR

The configurations and conformational features of N-H and N-vinyl-4,5,7-trimethyl-4,5,6,7-tetrahydropyrrolo[3,2-c]pyridines and their nitro derivatives were established by the method of 1H and 13C NMR spectroscopy. It was shown that the conformational uniformity of the piperideine ring in the compounds studied is strongly dependent on the character of the substituents in the pyrrole ring. A method for the determination of the orientation of the substituent at the α-position to the nitrogen atom of the piperideine ring, according to the direct 1JCH SSCC, was proposed. © 1993 Plenum Publishing Corporation.