Antimicrobial Activity of Nitrofural in Various Dosage Forms

The antimicrobial activities of nitrofural preparations were compared using diffusion in agar. Growth inhibition zones of microorganisms due to gels and solutions containing solid dispersions of nitrofural with active ingredient concentrations of 0.02 and 0.04% and furacilin ointment (0.2%) were determined. The test strains were Staphylococcus aureus, S. epidermis, and Escherichia coli. The experimental results led to the conclusion that preparations containing nitrofural solid dispersion had greater antimicrobial activity than those available on the pharmaceutical market. © 2020, Springer Science+Business Media, LLC, part of Springer Nature.