In the current study a sensory function of the periodontium of anterior teeth was examined during stages of prosthetic treatment with block and single prostheses for patients with a healthy periodon-tium through the method we developed (test for “food holding and splitting”) and the “Periosensomer” de-vice. We found out that during certain stages of prosthetic treatment in cases with anesthesia and fixation of temporary mouth guards connected into blocks, the sensory function of the periodontium is decreased up to 3-4. It can be either restored after fixation of permanent single prosthesis (e.g. veneers) and single crowns or remain reconstructed with fixation of permanent dental bridges and crowns based on implants. Howev-er, it should be noted that these nosy function is restored when the defect is replaced by dental crowns sup-ported by implants, while maintaining the vitality of the lateral teeth in the area of the defect. Hence, as a result of the usage of block prostheses and due to a decrease of the sensory function of the periodontal leads to masticatory pressure increase and a functional overload of the teeth included in the block and their an-tagonists with all the ensuing complications. An assessment of the periodontal sensory function of the periodontal membrane receptors and the dynamics of sensory response can be used as a method of functional diagnostics in the clinic of dental implantation and aesthetic prosthetics. © 2022, Colegio de Farmaceuticos de la Provincia de Buenos Aires. All rights reserved.