Influence of the choice of anesthetic aid on changes in the frequency range of heart rate variability during septoplasty in the early postoperative period

Objective. To assess the effect of the choice of anesthetic aid on changes in heart rate variability during septoplasty in the early postoperative period. Patients and methods. The study included 291 patients who underwent septoplasty for deviated septum. All patients received local anesthesia with 2% procaine solution. In group 1 (105 people) premedication was used with a 2% solution of promedol and 60 mg of ketorolac in the evening, in group 2 (108 people) — fentanyl, propofol, cisatracuria besylate, tranexamic acid, atropine and metoclopramide, in group 3 (78 people) — atracurium besylate, sodium thiopental, nitrous oxide and halothane. In groups 2 and 3, 100 mg of ketoprofen was administered intramuscularly in the evening on the day of surgery. For anterior nasal tamponade, all patients used foam tampons with a rubber glove. Holter ECG monitoring was performed daily. Heart rate variability was assessed: ULF, VLF, VHF, LF, HF and total power. Results. ULF and LF were significantly higher in groups 2 and 3 than in the local anesthetic group. VLF in the second group was significantly lower than in groups 1 and 3. Groups 2 and 3 had low HF, compared with group 1. The VHF of group 2 was significantly lower than in groups 1 and 3, which also differed from each other — the VHF values in group 1 were higher than in group 2. power in group 2 was significantly lower than in groups 1 and 3. However, the total power of the 3rd group was significantly higher than that of the 1st group. Conclusion. General anesthesia (fentanyl, propofol, cisatracuria besylate, tranexamic acid, atropine, and metoclopramide) may be among the presented methods of anesthesia for septoplasty for routine use. © 2022, Media Sphera Publishing Group. All rights reserved.