Prevention of endometrial hyperplasia without atypia in women of reproductive age [Профилактика гиперплазии эндометрия без атипии у женщин репродуктивного возраста]

Objective of this review is a systematic analysis of the data available in the current literature on the efficacy and safety of progestogens for the prevention of atypical endometrial hyperplasia (EH) in patients of reproductive age. EH is an excessive proliferation that results in increased volume and changes in endometrial tissue architectonics with an increase in the endometrial glands to stroma ratio of more than 1:1. This review will consider the use of progestogens for the prevention of (EH) based on evidence-based scientific evidence over the past 5 years. The expansion of the range of effective treatment options allows the adaptation of treatment to the needs of patients and offers a personalized approach to their management. Progestogens are an effective and safe method for the prevention of atypical hyperplasia, with a wide range of therapeutic benefits associated with reliable favorable fertility prognosis, especially in young women. © 2021 New Terra Publishing House. All rights reserved.

Authors
Orazov M.R. 1 , Mihaleva L.M.2 , Orekhov R.E. 1 , Mullina I.A. 1
Publisher
Общество с ограниченной ответственностью Медицинское маркетинговое агентство МедиаМедика
Number of issue
5
Language
Russian
Pages
454-458
Status
Published
Volume
23
Year
2021
Organizations
  • 1 People’s Friendship University of Russia, Moscow, Russian Federation
  • 2 Avtsyn Research Institute of Human Morphology, Moscow, Russian Federation
Keywords
DlyJens pro; Endometrial hyperplasia; Progestogens
Date of creation
06.07.2022
Date of change
06.07.2022
Short link
https://repository.rudn.ru/en/records/article/record/84789/
Share

Other records

Yarmolinskaya M.I., Radzinsky V.E., Orazov M.R., Korotkikh I.N., Ziganshin O.R., Eremina N.A., Khobets V.V.
Гинекология. Общество с ограниченной ответственностью Медицинское маркетинговое агентство МедиаМедика. Vol. 23. 2021. P. 392-401