Therapy challenges in patients with Mycoplasma genitalium infection of the urogenital tract: Clinical observations [Проблемы терапии больных с поражением мочеполовых органов Mycoplasma genitalium: клинические наблюдения]

Mycoplasma genitalium is a clinically significant intracellular bacterium from the family of genital mycoplasmas; it ab- solutely dominates in persistent/recurrent nongonococcal urethritis, causes chronic inflammatory diseases of the urogenital organs which dictates the necessity of treating this infection. The study presents observations of 2 patients with chronic recurrent urethritis caused by multiple drug resistant strains of M. genitalium. None of the administered schemes of antibacterial treatment covered in the international protocols on treatment of M. genitalium infection allowed to achieve clinical or microbiological cure in these patients. Practicing doctors require development and improvement of nucleic acid amplification methods with antimicrobial testing for M. genitalium resistance and new antimicrobial drugs with improved chemical and pharmacological characteristics for treatment of patients with intracellular urogenital infections. © 2021 ABC-press Publishing House. All Rights Reserved.