Recent Advances in Combinations of TLC With MALDI and Other Desorption/Ionization Mass-Spectrometry Techniques

The combination of planar chromatography with desorption/ionization mass-spectrometry (MS) techniques provides chemists with unique tools for fast and simple separation of mixtures followed by the detection of analytes by the most powerful analytical method. Since its introduction in the early 1990s, thin-layer chromatography (TLC)/matrix-assisted mass spectrometry (MALDI) has been used for the analysis of a wide range of analytes, including natural and synthetic organic compounds. Nowadays, new desorption/ionization approaches have been developed and applied in conjunction with planar chromatography competing with MALDI. This review covers recent developments in the combination of TLC with various desorption/ionization MS methods which were made in recent several years. Copyright © 2021 Borisov, Kanateva and Zhilyaev.

Authors
Borisov R. 1, 2 , Kanateva A.1 , Zhilyaev D. 1, 2
Journal
Frontiers in Chemistry
Publisher
Frontiers Media S. A
Language
English
Status
Published
Link
External link
DOI
10.3389/fchem.2021.771801
Number
771801
Volume
9
Year
2021
Organizations
  • 1 A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences, Moscow, Russian Federation
  • 2 Peoples Friendship University of Russia (RUDN University, Moscow, Russian Federation
Keywords
ambient ionization mass spectrometry (AIMS); derivatization; MALDI; sorbents; TLC
Date of creation
06.07.2022
Date of change
06.07.2022
Short link
https://repository.rudn.ru/en/records/article/record/84475/
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