A Comparative Analysis of Different Strains of Coronavirus Based on Genometric Mappings

Coronaviruses are viruses that infect the respiratory system of humans. Besides high mortality rates among the population, they brought about several economic crises on a global scale. Methods. To study and identify features in the genetic composition of the nucleotide sequences of various coronaviruses, we applied copyright algorithms and visualization, which allowed us to compare the biochemical parameters of diverse RNA coronaviruses in a visual form. Results. The article provides examples of different approaches to imaging coronaviruses. We have provided examples of coronavirus RNA structure visualization in various parametric spaces (1‐D and 2‐D). We employed various visualization types, including structural, integral, and frequency. The research discussed methods of visualization. Our team developed visualization and comparative analysis of coronavirus serotypes and visualization of SARS‐CoV‐2 coronavirus datasets. Discussion followed on the visualization results. The presented techniques and the results allowed for displaying the structure of RNA sequences of coronaviruses in spaces of various dimensions. Conclusions. According to our findings, the proposed method contributes to the visualization of the genetic coding of coronaviruses. We discussed the issues of machine learning and neural network technology concerning the analysis of coronaviruses based on the presented approach. The described line of research is essential for the study and control of complex quantum mechanical systems, such as RNA or DNA. © 2022 by the authors. Licensee MDPI, Basel, Switzerland.

Authors
Stepanyan I.V. 1, 2 , Lednev M.Y.1
Journal
Publisher
MDPI AG
Number of issue
5
Language
English
Status
Published
Number
942
Volume
14
Year
2022
Organizations
  • 1 Mechanical Engineering Research Institute of the Russian Academy of Sciences (IMASH RAN), M. Kharitonyevskiy Pereulok, Moscow, 101990, Russian Federation
  • 2 Peoples’ Friendship, University of Russia (RUDN University), 6 Miklukho‐Maklaya Street, Moscow, 117198, Russian Federation
Keywords
coronavirus; fractal geometry; HCoV; machine learning; RNA; symmetries; visualization
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