Prospects for the use of photodynamic method in the complex treatment of bladder cancer

Constant growth of incidence rate of bladder cancer (BC) requires refinement of methods of early diagnostics and development of efficient treatment methods. Diagnostics and adjuvant photodynamic therapy (PDT) with the use of light and photosensitizer drugs (PD) of surface transitional cell (STC) BC are not sufficiently investigated. 40 persons aged 23 - 87 suffering from STC BC took part in the research and were subjected to complex therapy (CT). STC BC patients of this group before the transurethral resection (TUR) were administered intravenously with PD, then photodynamic diagnostics (PDD) of disease focuses was performed. Control group consisted of 15 patients with BC of the same age category, for treatment of which only TUR was used. It was established that the use of CT for STC BC contributed to decrease of relapse rate and progression of disease, increase of specific survival and quality of life of patients.

Authors
Salnikova S. 2, 3 , Slavyanskaya T. 2, 1 , Ivanchenko L.3 , Baldueva I.4
Publisher
FILODIRITTO PUBLISHER
Language
English
Pages
303-309
Status
Published
Year
2016
Organizations
  • 1 Peoples Friendship Univ Russia, Moscow, Russia
  • 2 Inst Immunophysiol, Moscow, Russia
  • 3 FSBI Clin Hosp 1 Presidential Affairs Management, Moscow, Russia
  • 4 Minist Healthcare Russian Federat, FSBI Petrov Res Inst Oncol, St Petersburg, Russia
Keywords
bladder cancer; photodynamic therapy; photodynamic diagnostics; urothelial carcinoma; transurethral resection; quality of life
Date of creation
19.10.2018
Date of change
19.10.2018
Short link
https://repository.rudn.ru/en/records/article/record/8148/
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