Rossiyskiy Vestnik Perinatologii i Pediatrii.
National Academy of Pediatric Science and Innovation.
Vol. 66.
2021.
P. 59-65
the influence of genetic factors on the effectiveness, safety and tolerability of antiretroviral therapy in patients with hiv infection
This article provides an overview of the existing literature on the pharmacogenetic determinants of exposure and toxicity of antiretroviral drugs, as well as on genetic markers associated with the rate of disease progression. In addition, this article looks at current clinical opportunities as well as genetics in HIV drug development. Large-scale, integrated approaches to the genome are expected to significantly change the knowledge landscape in the future. © 2021 Interregional public organization Association of infectious disease specialists of Saint-Petersburg and Leningrad region (IPO AIDSSPbR). All rights reserved.
Authors
Kanestri V.G.1,
2
,
Shakhgildyan V.I.1,
2
,
Kravchenko A.V.
1,
2
,
Konnov D.S.
1
,
Popova A.A.
1,
2,
3
Journal
Publisher
Interregional public organization Association of infectious disease specialists of Saint-Petersburg and Leningrad region (IPO AIDSSPbR)
Number of issue
1
Language
Russian
Pages
21-28
Status
Published
Link
Volume
13
Year
2021
Organizations
- 1 Central Research Institute of Epidemiology, Moscow, Russian Federation
- 2 University Clinic «H-Clinic», Moscow, Russian Federation
- 3 Peoples Friendship University of Russia, Moscow, Russian Federation
Keywords
Comorbidities; Genetic; HIV infection; Opportunistic infections
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