X-ray is a highly demanded therapy method with wide clinical indications. The high operational efficiency of such equipment makes it possible to ensure the accessibility of medical care. Taking into account the current healthcare trend towards patient-oriented principles of work, it is necessary to evaluate medical organizations and their units for compliance with these principles. Purpose of the study: To assess the implementation of patient-oriented principles in the work of the X-ray therapy service of the City Mariinsky Hospital. Objectives of the research: To analyze the organizational conditions of the X-ray therapy service, to study the structure and dynamics of patients and make conclusions about the implementation of the principles of patient-oriented principles of work. Material and methods. The activity of the X-ray therapy was assessed from the patient-oriented approach. The methods of bibliographic and informational search of sources in document databases, as well as semantic search on the Internet were used. Results: The hospital's Xray therapy service demonstrates high rates of operational efficiency, providing in a short time high rate of access to the X-ray therapy for patients with different nosology. It's work meets most of the criteria for patient-centered work - the proximity of medical care to the patient, orientation towards respectful attitude to the values and needs of patients, rational use of available technical, time and human resources. For further improvement of work in accordance with the principles of patient orientation, it is necessary to introduce formalized questionnaires of the quality of life and assess the quality of medical services. Conclusion. The presented analysis is the first comprehensive multicriteria study of the patient-centered work of the X-ray therapy service in Russia. © 2021 State Research Center, Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. All rights reserved.