AIM: The aim of this work is to increase the quality and accuracy of the prostheses manufacture on implants in patients with completely absent dentition, to reduce the number of doctors’ visits to creation of temporary crowns, and more quickly adapt to new prostheses. MATERIALS AND METHODS: A survey and comprehensive treatment of 55 people with complete edentulousness were carried out. Group I consisted of 30 patients who underwent treatment using the developed prototyping method, which took into account the shape of the complete removable dentures and the ratio of the jaws during the manufacture of the prosthesis on implants. The treatment of Group II, consisting of 25 patients, was carried out using a standard technique-after opening the implants, the central ratio of the jaws and the setting of the teeth were re-determined. RESULTS: The treatment of patients with completely absent dentition using the developed prototyping methodology allowed to increase the accuracy of manufacturing temporary dentures based on dental implants, reduce the time of adaptation to the prosthesis and achieve high aesthetic results. CONCLUSION: A prosthesis made using the proposed methodology for transferring the parameters of a temporary dentures to a permanent ones based on dental implants meets all functional and aesthetic requirements, improves the quality of prosthetics, reduces the manufacturing time of the prosthesis, the patient’s adaptation time to it, and is the basis for improving the quality of patient’s life. © 2021 Igor Kladnichkin, Sergej Ivanov, Valerij Bekreev, Vadim Dmitrievich Trufanov, Galina Brkich.