The large and massive rotator cuff tears lead to a significant decrease in the shoulder joint (SJ) function and the development of severe pain syndrome in it. Frequently, such injuries are difficult to recover fully, and the number of relapses after their recovery is quite high. The combined method of rotator cuff repair single-row suture anchor technique with concomitant use of a subacromial balloon spacer, allows to achieve the best results in the treatment of this group of patients. Objective - improvement of the treatment results in patients with large and massive rotator cuff injuries. The results of treatment using a single-row suture anchor technique with concomitant use of a subacromial balloon spacer have been described in 25 patients (mean age 58±5 years) with large and massive rotator cuff injuries. In the study were involved the patients with 1-2 grade of fatty muscle atrophy according to the Goutallier classification, and retraction of the damaged tendons did not exceed 2 degrees. The mean UCLA activity scores prior to the surgery was 16±3 points (15-19), and in 12 months after the surgery 33±1 points (32-34), respectively. All the results obtained were regarded as: good and excellent. The obtained results evidence the advantage of the combined method of rotator cuff repair by insulated suture.