The potential of nuclear magnetic resonance (NMR) in metabolomics and lipidomics of microalgae- a review

Microalgae biotechnology has made it possible to derive secondary bioactive metabolites from microalgae strains that have opened up their entire potential to uncover a wide range of novel metabolic capabilities and turn these into bio-products for the development of sustainable bio-refineries. Nuclear Magnetic Resonance Technology (NMR) has been one of the most successful and functional research technology over the past two decades to analyse the composition, structure and functionality of distinct metabolites in the different microalgae strains. This technology offers qualitative as well as quantitative knowledge about the endogenous metabolites and lipids of low molecular mass to offer a good picture of the physiological state of biological samples in metabolomics and lipidomics studies. Henceforth, this review is aimed at introducing the metabolomics and lipidomics studies into the field of NMR technology and also highlights the protocols for the isolation and metabolic measurements of metabolites from microalgae that should be redirected to resource recovery and value-added products with a systematic and holistic approach for scalability or sustainability. © 2021 Elsevier Inc.

Authors
Bisht B.1 , Kumar V. 2, 3 , Gururani P.4 , Tomar M.S.5 , Nanda M.6 , Vlaskin M.S.7 , Kumar S.2 , Kurbatova A. 8
Journal
Archives of Biochemistry and Biophysics
Publisher
Academic Press Inc.
Language
English
Status
Published
Link
External link
DOI
10.1016/j.abb.2021.108987
Number
108987
Volume
710
Year
2021
Organizations
  • 1 Department of Post-Harvest Process and Food Engineering, G. B. Pant University of Agriculture and Technology, Pantnagar, Uttarakhand, India
  • 2 Department of Life Sciences, Graphic Era (Deemed to Be University), Dehradun, Uttarakhand 248002, India
  • 3 Peoples’ Friendship University of Russia (RUDN University), Moscow, 117198, Russian Federation
  • 4 Department of Biotechnology, Graphic Era (Deemed to Be University), Dehradun, Uttarakhand 248002, India
  • 5 Department of Food Process Engineering, National Institute of Technology, Rourkela, India
  • 6 Department of Biotechnology, Dolphin (PG) Institute of Biomedical and Natural Sciences, Dehradun, Uttarakhand 248007, India
  • 7 Joint Institute for High Temperatures of the Russian Academy of Sciences, 13/2 Izhorskaya St, Moscow, 125412, Russian Federation
  • 8 Department of Environmental Monitoring and Forecasting, Ecological Faculty, RUDN University, Moscow, 117198, Russian Federation
Keywords
Biotechnology; Lipidomics; Metabolomics; Microalgae; NMR; Sustainable
Date of creation
16.12.2021
Date of change
25.08.2023
Short link
https://repository.rudn.ru/en/records/article/record/76561/
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