In our study we used concrete modifier MB10-01, an admixture on an organic-mineral basis contained of micro-silica, fly ash, hardening regulator, and superplasticizer, to produce the high-strength coarse-aggregate concrete (HSCAC) with compressive strength of more than 100 MPa. We produced samples of HSCAC with dimensions of 100x100x100 mm and 100x100x450 mm. The physical and mechanical properties of HSCAC, such as: compressive strength, tensile strength at bending, strength at axial tension, cracking moment and HSCAC grade, at the curing periods of 7, 14, 28, 60 days, have been determined. The research results have been implemented in the construction of high-rise buildings of the Moscow International Business Center "Moscow City", and in reconstruction of the Engineering Faculty building of the RUDN University.