Comparative results of surgical, combined and comprehensive treatment of newly onset medulloblastoma in children

The authors present the outcomes of treatment of 107 patients with histologically verified diagnosis of medulloblastoma. Of these, 22 children were subjected only to surgical treatment, 25 – operative and radiotherapy, and 60 – polychemotherapy as a stage of a comprehensive or combined treatment. It was determined that survival of children with medulloblastoma was influenced by such factors as the presence of polychemotherapy and radiotherapy, a residual tumour following nonradical removal thereof, involvement of the brain stem into the tumour process, as well as tumour cells in the lumbal liquor. Carrying out ventriculoperitoneal by-pass decreases survival of patients with medulloblastoma. © 2002, Fund - Doctors, Innovations,Science for Children. All rights reserved.

Authors
Lifshits M.I.1 , Zheludkova O.G.2 , Voronyuk G.M.1 , Rumyantsev A.G.2 , Popov V.E. 1 , Gorbatykh S.V.1 , Andreeva E.V.1 , Rotar M.G.1 , Manzhos P.I. 1 , Gorelyshev S.K.3 , Prityko A.G. 5 , Palm V.V.4 , Bychkov V.A.1 , Umerenkov V.N.1 , Gorbunov V.A.1 , Leonovich A.E.1 , Belogurova M.B.2
Journal
Вопросы гематологии/онкологии и иммунопатологии в педиатрии
Publisher
Фонд поддержки и развития в области детской гематологии, онкологии и иммунологии Врачи, инновации, наука - детям
Number of issue
1
Language
Russian
Pages
84-90
Status
Published
Link
External link
Volume
1
Year
2002
Organizations
  • 1 Morozov Children’s Municipal Clinical Hospital, Moscow, Russian Federation
  • 2 Research Institute of Paediatric Haematology, Russian Federation Health Ministry, Moscow, Russian Federation
  • 3 N.N. Burdenko Research institute of Neurosurgery, Moscow, Russian Federation
  • 4 Russian Children’s Clinical Hospital, Moscow, Russian Federation
  • 5 Russian University of Friendship of Peoples, Moscow, Russian Federation
Keywords
Children; Medulloblastoma; Operative treatment; Polychemotherapy; Radiotherapy; Residual tumour
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