Multicomponent synthesis of nicotinic acid derivatives

[Figure not available: see fulltext.] The synthesis of previously unknown nitriles, esters, and an amide of 6-alkoxy-2-alkylsulfanyl-4-methyl(4,4-dimethyl)nicotinic acid has been developed. The structure of a number of the obtained derivatives was proved by X-ray structural analysis. © 2021, Springer Science+Business Media, LLC, part of Springer Nature.

Authors
Dyachenko I.V.1 , Dyachenko V.D.1 , Dorovatovskii P.V. 2 , Khrustalev V.N. 3, 4 , Nenajdenko V.G. 5
Journal
Chemistry of Heterocyclic Compounds
Publisher
Латвийский институт органического синтеза Латвийской академии наук / Springer New York Consultants Bureau
Number of issue
12
Language
English
Pages
1579-1585
Status
Published
Link
External link
DOI
10.1007/S10593-020-02852-9
Volume
56
Year
2020
Organizations
  • 1 Luhansk Taras Shevchenko National University, 2 Oboronna St., Lugansk, 91000, Ukraine
  • 2 National Research Center “Kurchatov Institute”, 1 Akademika Kurchatova Sq., Moscow, 123182, Russian Federation
  • 3 RUDN University, 6 Miklukho-Maklaya St., Moscow, 117198, Russian Federation
  • 4 N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky Ave., Moscow, 119991, Russian Federation
  • 5 Lomonosov Moscow State University, 1, Build. 3 Leninskie Gory, Moscow, 119991, Russian Federation
Keywords
6-alkoxy-2-alkylsulfanyl-4-methyl(4,4-dimethyl)nicotinic acid; alkylation; Michael reaction; multicomponent synthesis; thiazolo[3,2-a]pyridines; X-ray structural analysis; СH acids
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