EAU-ESMO consensus statements on the management of advanced and variant bladder cancer-an international collaborative multi-stakeholder effort: under the auspices of the EAU and ESMO Guidelines Committees†

Horwich A.¹ , Babjuk M.^{2, 3} , Shariat S.F.^{2, 3, 20, 21, 22} , Santis M.D.^{3, 8} , Grubmüller B.³ , Remzi M.³ , Vartolomei M.D.^{3, 126} , Bellmunt J. ^{4, 5} , Bruins H.M.⁶ , Brummelhuis I.⁶ , Smits A.⁶ , Van Der Heijden A.G.⁶ , Witjes J.A.⁶ , Reijke T.M.D.⁷ , Oddens J.R.⁷ , Gillessen S.^{9, 10, 11, 12} , Birtle A. ^{9, 29} , Choudhury A.^{9, 10} , Hoskin P.^{9, 10, 68} , James N.^{13, 14} , Maclennan S.¹⁵ , N'Dow J.^{15, 51} , Palou J.¹⁶ , Huguet J.¹⁶ , Powles T.^{17, 18} , Ribal M.J.¹⁹ , Vilaseca A.¹⁹ , Bochner B.H.^{20, 31} , Kwast T.V.D.²³ , Xylinas E.^{24, 25} , Agarwal N.²⁶ , Arends T.²⁷ , Bamias A.²⁸ , Black P.C.³⁰ , Herr H.³¹ , Bolla M.³² , Boormans J.L.³³ , Bossi A.³⁴ , Briganti A.^{35, 36} , Burger M.³⁷ , Castellano D.³⁸ , Cathomas R.³⁹ , Chiti A.^{40, 41} , Oyen W.J.G.^{40, 41, 56, 95} , Compérat E.^{42, 43} , Crabb S.⁴⁴ , Culine S.⁴⁵ , Bari B.D.^{46, 47} , Blok W.D.⁴⁸ , De Visschere P.J.L.⁴⁹ , Decaestecker K.⁵⁰ , Dimitropoulos K.⁵¹ , Dominguez-Escrig J.L.⁵² , Mir M.C.⁵² , Fanti S.⁵³ , Fonteyne V.⁵⁴ , Frydenberg M.⁵⁵ , Futterer J.J.⁵⁶ , Gakis G.⁵⁷ , Geavlete B.⁵⁸ , Gontero P. ⁵⁹ , Hafeez S.^{60, 61} , Khoo V.^{60, 61, 73, 74} , Hansel D.E.⁶² , Hartmann A.⁶³ , Hayne D.⁶⁴ , Henry A.M.⁶⁵ , Hernandez V.⁶⁶ , Herrmann K.⁶⁷ , Jereczek-Fossa B.A.^{69, 70} , Jones R.⁷¹ , Kamat A.M.⁷² , Kiltie A.E.⁷⁵ , Krege S.⁷⁶ , Ladoire S.⁷⁷ , Lara P.C.^{78, 79} , Leliveld A.⁸⁰ , Linares-Espinós E.⁸¹ , Løgager V.⁸² , Lorch A.⁸³ , Loriot Y.⁸⁴ , Meijer R.⁸⁵ , Moschini M. ⁸⁶ , Mostafid H.⁸⁷ , Müller A.C. ⁸⁸ , Müller C.R.⁸⁹ , Necchi A.⁹⁰ , Neuzillet Y.⁹¹ , Oldenburg J.^{92, 93} , Osanto S.⁹⁴ , Pacheco-Figueiredo L.^{96, 97} , Pappot H.⁹⁸ , Patel M.I.⁹⁹ , Pieters B.R.¹⁰⁰ , Plass K.¹⁰¹ , Retz M.¹⁰² , Richenberg J.^{103, 104} , Rink M.¹⁰⁵ , Roghmann F.¹⁰⁶ , Rosenberg J.E.^{107, 108} , Rouprêt M.¹⁰⁹ , Rouvière O.^{110, 111} , Salembier C.¹¹² , Salminen A.¹¹³ , Sargos P.¹¹⁴ , Sengupta S.^{115, 116} , Sherif A.¹¹⁷ , Smeenk R.J.¹¹⁸ , Stenzl A.¹¹⁹ , Thalmann G.N.¹²⁰ , Tombal B. ¹²¹ , Turkbey B.¹²² , Lauridsen S.V.¹²³ , Valdagni R.¹²⁴ , Van Poppel H.¹²⁵ , Veskimäe E.¹²⁷ , Rivera F.A.V.¹²⁸ , Wiegel T.¹²⁹ , Wiklund P.^{130, 131} , Williams A.⁸⁶ , Zigeuner R.¹³²

Annals of Oncology

Oxford University Press

11

English

1697-1727

Published

30

2019

• ¹ Institute of Cancer Research
• ² Depatment of Urology|2nd Faculty of Medicine|Hospital Motol|Charles University
• ³ Department of Urology|Medical University of Vienna
• ⁴ Department of Urology|Weill Cornell Medical College
• ⁵ Department of Urology|University of Texas Southwestern Medical Center
• ⁶ Institute for Urology and Reproductive Health|I.M. Sechenov First Moscow State Medical University
• ⁷ Department of Urology|Charité University Hospital
• ⁸ Department of Cell and Molecular Biology|George Emil Palade University of Medicine|Pharmacy|Science|Technology of Targu Mures
• ⁹ IMIM-Hospital del Mar Medical Research Institute
• ¹⁰ Harvard Medical School
• ¹¹ Department of Urology|Radboud University Medical Center
• ¹² Department of Urology|Amsterdam University Medical Centers|University of Amsterdam
• ¹³ Division of Cancer Sciences|University of Manchester
• ¹⁴ Christie NHS Foundation Trust
• ¹⁵ Division of Oncology and Haematology
• ¹⁶ University of Bern
• ¹⁷ Rosemere Cancer Centre|Lancashire Teaching Hospitals
• ¹⁸ Mount Vernon Centre for Cancer Treatment
• ¹⁹ University Hospitals Birmingham NHS Foundation Trust
• ²⁰ Institute of Cancer and Genomic Sciences|University of Birmingham
• ²¹ Academic Urology Unit|University of Aberdeen
• ²² Department of Urology|Aberdeen Royal Infirmary
• ²³ Department of Urology|Fundació Puigvert|Universitat Autònoma de Barcelona
• ²⁴ Royal Free NHS Trust
• ²⁵ Barts Cancer Institute|Queen Mary University of London
• ²⁶ Uro-Oncology Unit|Hospital Clinic|University of Barcelona
• ²⁷ Urology Service|Department of Urology|Memorial Sloan Kettering Cancer Center
• ²⁸ Department of Pathology|Erasmus Medical Center
• ²⁹ Department of Urology|Bichat-Claude Bernard Hospital
• ³⁰ Paris Descartes University
• ³¹ Huntsman Cancer Institute|University of Utah (NCI-CCC)
• ³² Urology Department|Canisius-Wilhelmina Ziekenhuis Nijmegen
• ³³ 2nd Propaedeutic Dept of Internal Medicine|Medical School|National & Kapodistrian University of Athens
• ³⁴ Department of Urologic Sciences|Vancouver Prostate Centre|University of British Columbia
• ³⁵ Emeritus Professor of Radiation Oncology|Grenoble - Alpes University
• ³⁶ Department of Urology|Erasmus University Medical Center
• ³⁷ Department of Radiation Oncology|Gustave Roussy Institute
• ³⁸ Department of Urology|Urological Research Institute
• ³⁹ Vita-Salute University|San Raffaele Scientific Institute
• ⁴⁰ Department of Urology|Caritas-St. Josef Medical Center|University of Regensburg
• ⁴¹ Medical Oncology Department
• ⁴² Department Innere Medizin|Abteilung Onkologie und Hämatologie|Kantonsspital Graubünden
• ⁴³ Department of Biomedical Sciences|Humanitas University
• ⁴⁴ Humanitas Research Hospital
• ⁴⁵ Department of Radiology and Nuclear Medicine|Radboud University Medical Center
• ⁴⁶ Department of Radiology and Nuclear Medicine|Rijnstate Hospital
• ⁴⁷ Department of Pathology|Tenon Hospital|HUEP
• ⁴⁸ Sorbonne University
• ⁴⁹ Cancer Sciences Unit|University of Southampton
• ⁵⁰ Department of Cancer Medicine|Hôpital Saint Louis
• ⁵¹ Radiation Oncology Department|Centre Hospitalier Régional Universitaire "Jean Minjoz" of Besançon|INSERM UMR 1098
• ⁵² Radiation Oncology Department|Centre Hospitalier Universitaire Vaudois|Université de Lausanne
• ⁵³ Department of Urology|University Medical Center Utrecht
• ⁵⁴ Department of Radiology and Nuclear Medicine|Division of Genitourinary Radiology and Mammography|Ghent University Hospital
• ⁵⁵ Department of Urology|Ghent University Hospital
• ⁵⁶ Servicio de Urología|Fundación Instituto Valenciano de Oncología
• ⁵⁷ Department of Nuclear Medicine|Policlinico S Orsola|University of Bologna
• ⁵⁸ Department of Radiotherapy Oncology|Ghent University Hospital
• ⁵⁹ Department of Surgery|Faculty of Medicine|Nursing and Health Sciences|Monash University
• ⁶⁰ Department of Urology and Paediatric Urology|University Hospital of Würzburg|Julius-Maximillians University|Würzburg
• ⁶¹ Department of Urology|Saint John Emergency Clinical Hospital
• ⁶² Division of Urology|Molinette Hospital|University of Studies of Torino
• ⁶³ Division of Radiotherapy and Imaging|Institute of Cancer Research
• ⁶⁴ Department of Clinical Oncology|Royal Marsden NHS Foundation Trust
• ⁶⁵ Department of Medicine|University of Melbourne
• ⁶⁶ Monash University
• ⁶⁷ Department of Urology|University of California|San Diego Pathology
• ⁶⁸ Institute of Pathology|Friedrich-Alexander University (FAU) Erlangen-Nürnberg
• ⁶⁹ Department of Urology|UWA Medical School|University of Western Australia
• ⁷⁰ Leeds Institute of Medical Research|University of Leeds
• ⁷¹ Department of Urology|Hospital Universitario Fundación de Alcorcón
• ⁷² Department of Nuclear Medicine|Universitätsklinikum Essen
• ⁷³ Department of Oncology and Hemato-oncology|University of Milan
• ⁷⁴ Division of Radiotherapy|IEO European Institute of Oncology|IRCCS
• ⁷⁵ Institute of Cancer Sciences|College of Medicine|Veterinary and Life Sciences|University of Glasgow
• ⁷⁶ Department of Urology - Division of Surgery|University of Texas|MD Anderson Cancer Center
• ⁷⁷ CRUK/MRC Oxford Institute for Radiation Oncology|University of Oxford
• ⁷⁸ Department of Urology|Pediatric Urology and Urologic Oncology
• ⁷⁹ Department of Medical Oncology|Centre Georges François Leclerc
• ⁸⁰ Department of Oncology|Hospital Universitario San Roque
• ⁸¹ Universidad Fernando Pessoa
• ⁸² Department of Urology|University Medical Center Groningen|University of Groningen
• ⁸³ Department of Urology|University Hospital La Paz
• ⁸⁴ Department of Radiology|Copenhagen University Hospital Herlev and Gentofte|Herlev
• ⁸⁵ Department of Medical Oncology and Hematology|University Hospital Zürich
• ⁸⁶ Département de Médecine Oncologique|Gustave Roussy|INSERM U981
• ⁸⁷ UMC Utrecht Cancer Center|MS Oncologic Urology
• ⁸⁸ Department of Urology
• ⁸⁹ Department of Urology|Royal Surrey County Hospital
• ⁹⁰ Department of Radiation Oncology|Eberhard Karls University|Tübingen
• ⁹¹ Cancer Treatment Centre|Sorlandet Hospital
• ⁹² Department of Medical Oncology|Istituto Nazionale Tumori of Milan
• ⁹³ Department of Urology|Hospital Foch|University of Versailles-Saint-Quentin-en-Yvelines
• ⁹⁴ Department of Oncology|Akershus University Hospital
• ⁹⁵ Faculty of Medicine|University of Oslo
• ⁹⁶ Department of Clinical Oncology|Leiden University Medical Center
• ⁹⁷ Department of Urology|Centro Hospitalar São João
• ⁹⁸ Life and Health Sciences Research Institute (ICVS)|School of Medicine|University of Minho
• ⁹⁹ Department of Oncology|Rigshospitalet|University Hospital of Copenhagen
• ¹⁰⁰ Department of Urology|University of Sydney
• ¹⁰¹ Department of Radiation Oncology|Amsterdam University Medical Centers|University of Amsterdam
• ¹⁰² EAU Guidelines Office
• ¹⁰³ Department of Urology|Rechts der Isar Medical Center|Technical University of Munich
• ¹⁰⁴ Department of Imaging and Nuclear Medicine|Royal Sussex County Hospital
• ¹⁰⁵ Brighton and Sussex Medical School
• ¹⁰⁶ Department of Urology|University Medical Center Hamburg-Eppendorf
• ¹⁰⁷ Department of Urology|Ruhr-University Bochum|Marien Hospital
• ¹⁰⁸ Department of Medicine|Memorial Sloan Kettering Cancer Center
• ¹⁰⁹ Weill Cornell Medical College
• ¹¹⁰ Department of Urology|Sorbonne Université|ONCOTYPE-URO|AP-HP|Hôpital Pitié-Salpêtrière
• ¹¹¹ Hospices Civils de Lyon|Service d'Imagerie Urinaire et Vasculaire|Hôpital Edouard Herriot
• ¹¹² Université de Lyon|Faculté de Médecine Lyon Est
• ¹¹³ Department of Radiation Oncology|Europe Hospitals Brussels
• ¹¹⁴ Department of Urology|University Hospital of Turku
• ¹¹⁵ Department of Radiotherapy|Institut Bergonié
• ¹¹⁶ Department of Surgery|University of Melbourne
• ¹¹⁷ Eastern Health Clinical School|Monash University
• ¹¹⁸ Department of Surgical and Perioperative Sciences|Urology and Andrology
• ¹¹⁹ Department of Radiation Oncology|Radboud University Medical Center
• ¹²⁰ Department of Urology|Eberhard Karls University Tübingen|Tübingen
• ¹²¹ Department of Urology|Inselspital|Bern University Hospital
• ¹²² Division of Urology|IREC|Cliniques Universitaires Saint Luc|UCL
• ¹²³ Molecular Imaging Program|National Cancer Institute
• ¹²⁴ Department of Urology|Rigshospitalet|Copenhagen University Hospital
• ¹²⁵ Department of Oncology and Hemato-oncology|Università degli Studi di Milano|Fondazione IRCCS Istituto Nazionale dei Tumori
• ¹²⁶ Department of Urology|University Hospitals Leuven
• ¹²⁷ Department of Urology|Tampere University Hospital
• ¹²⁸ Universidad Metropolitana|Clinica Club de Leones
• ¹²⁹ Department of Radiation Oncology
• ¹³⁰ Icahn School of Medicine
• ¹³¹ Department of Urology|Karolinska Institutet
• ¹³² Department of Urology|Medizinische Universität Graz