The goal of the paper is to argue and to develop a conceptual pedagogical model of formation of teacher's readiness for the development of systems thinking. The challenges of this paper are to analyze domestic and foreign psychological and pedagogical literature on the problem of teacher's readiness for the development of systems thinking, to summarize the results available in domestic and foreign literature, to argue methodological approaches and principles in the process of training a conceptual pedagogical model. The systems state of modern science has a theoretical potential for serious enriching and developing the priority trends in the field of science, technology, Economics and education are characterized by a number of specific features, the need to understand the complex economic processes initiated by scientific progress. The center of integrative approaches in connection with the globalization of education is the training of a new format teacher. This is primarily due to the lack of relationship between the requirements of the FSES and the problem of teacher's readiness to work with a huge amount of information, the ability to identify practice-oriented professional information in terms of incompleteness and inconsistency, to systemsatize it for the goal of its further realization in the educational process. Since natural sciences have a huge potential aimed at the development of systems thinking as a personal quality of a teacher, it leads to the need to investigate the problem of teacher's readiness for the development of systems thinking. In modern conditions it is impossible to imagine professionally, culturally and psychologically adapted teacher for professional work and vital activity with minimal cost, clearly expressed knowledge, awareness of perception of professional knowledge, independence, and depth judgments, ability to establish comfortable relations of the subjects of education, to work in a team.