A novel method for the extraction of the main compounds from the essential oil of clove buds

The purpose of this work was to test a hypothesis about the possibility of extraction of the main clove buds essential oil substances from with two different types of perfluoro organic solvents, Novec 1230 and Novec 7100. Using simple maceration method, it was found out that the maximum yield of eugenol was observed into n-hexane: 81 ± 4%. The yield of eugenol into perfluoro organic solvent Novec 7100 was 73 ± 4% and into the perfluoro organic solvent Novec 1230 was 6.9 ± 0.4%. Using the extraction circulation method, it was found that the yield of eugenol into perfluoro organic solvent Novec 7100 in 2 h of circulation was 85 ± 4%. Under the same conditions, the yield of eugenol into the perfluoro organic solvent Novec 1230 was 54 ± 3% during 4 h of its circulation. © 2020, Romanian Society for Pharmaceutical Sciences. All rights reserved.

Authors
Boyko N.N.1, 2 , Zhilyakova E.T.2 , Pisarev D.I. 3 , Novikov O.O. 3 , Sahaidak-Nikitiuk R.V.4 , Kuznietsova V.Y.U.5 , Shpychak O.S.6 , Tkachev A.V.7 , Kovalenko A.M.8 , Sushchuk N.A.9
Journal
Farmacia
Publisher
Romanian Society for Pharmaceutical Sciences
Number of issue
1
Language
English
Pages
170-175
Status
Published
Link
External link
DOI
10.31925/farmacia.2020.1.24
Volume
68
Year
2020
Organizations
  • 1 Laboratory of Technology of Drugs, Belgorod National Research University, 85 Pobedy Street, Belgorod, Russian Federation
  • 2 Department of Pharmaceutical Technology, Belgorod National Research University, 85 Pobedy Street, Belgorod, Russian Federation
  • 3 Shared Knowledge Center (Research and Educational Center) “Drugs’ quality control center” Рeoples’ Friendship University of Russia, 8/2 Miklukho-Maklay Street, Moscow, Russian Federation
  • 4 Department of Processes and Apparatuses of Chemical and Pharmaceutical Industries, National University of Pharmacy, 53 Pushkinska Street, Kharkiv, Ukraine
  • 5 Department of Chemistry of Natural Compounds, National University of Pharmacy, 53 Pushkinska Street, Kharkiv, Ukraine
  • 6 Department of Industrial Pharmacy and Economy Institute for Advanced Training of Pharmacy Specialists, National University of Pharmacy, 53 Pushkinska Street, Kharkiv, Ukraine
  • 7 Department of General and Private Zootechnics, Belgorod State Agricultural University named after V. Gorin, Federal State Budgetary Educational Institution of Higher Education, 3 Vavilova Street, Belgorod, Russian Federation
  • 8 Department of Infectious and Invasive Pathology, Belgorod State Agricultural University named after V. Gorin, Federal State Budgetary Educational Institution of Higher Education, 3 Vavilova Street, Belgorod, Russian Federation
  • 9 Department of Technology of Drugs, Odessa National Medical University, 2 Valikhovsky Lane, Odessa, Ukraine
Keywords
Clove buds; Eugenol; Novec 1230; Novec 7100
Date of creation
02.11.2020
Date of change
02.11.2020
Short link
https://repository.rudn.ru/en/records/article/record/65606/
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