The work is devoted to obtaining explicit formulas for analytic continuation of quite general hypergeometric series depending on three variables and belonging to the Horn class. We have derived such continuation formulas with respect to one variable for an arbitrary series belonging to the class under consideration. In addition, on the base of several examples we have demonstrated the use of the obtained formulas for construction of analytic continuation with respect to all three variables. The obtained continuation formulas give representations for a triple hypergeometric series outside the domain of its convergence in the form of a combination of other hypergeometric series that also belong to the Horn class. These series satisfy to the same system of partial differential equations as the initial series. The results of the paper are useful for qualitative analysis and calculation of triple hypergeometric functions. © 2020 Informa UK Limited, trading as Taylor & Francis Group.