Antimicrobial Activity of Nitrofural in Various Dosage Forms

The antimicrobial activities of nitrofural preparations were compared using diffusion in agar. Growth inhibition zones of microorganisms due to gels and solutions containing solid dispersions of nitrofural with active ingredient concentrations of 0.02 and 0.04% and furacilin ointment (0.2%) were determined. The test strains were Staphylococcus aureus, S. epidermis, and Escherichia coli. The experimental results led to the conclusion that preparations containing nitrofural solid dispersion had greater antimicrobial activity than those available on the pharmaceutical market. © 2020, Springer Science+Business Media, LLC, part of Springer Nature.

Authors
Kashlikova I.M. 1, 3 , Belyatskaya A.V. 1, 3 , Krasnyuk I.I.Jr. , Krasnyuk I.I. 1, 3 , Voropaeva E.A. 3, 2 , Egorova E.A. 3, 2 , Stepanova O.I. 1, 3 , Vorob’yov A.N. 1, 3
Journal
Pharmaceutical Chemistry Journal
Number of issue
1
Language
English
Pages
57-60
Status
Published
Link
External link
DOI
10.1007/s11094-020-02155-5
Volume
54
Year
2020
Organizations
  • 1 I. M. Sechenov First Moscow State Medical University of the Ministry of Health of the RF (Sechenov University), Moscow, 119991, Russian Federation
  • 2 G. N. Gabrichevsky Moscow Scientific Research Institute of Epidemiology and Microbiology, Moscow, 125212, Russian Federation
  • 3 People’s Friendship University of Russia, Moscow, 117198, Russian Federation
Keywords
furacilin; gels; nitrofural; solid dispersions
Date of creation
02.11.2020
Date of change
02.11.2020
Short link
https://repository.rudn.ru/en/records/article/record/64879/
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